Stefan M Pfister Selected Research

Phosphotransferases (Kinase)

1/2021	Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma.
1/2020	Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.
10/2018	Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.
1/2018	Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation-the NCT Neuro Master Match (N2M2) pilot study.
1/2018	Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.
10/2016	FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
1/2015	Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.

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Stefan M Pfister Research Topics

Disease

161	Neoplasms (Cancer) 01/2022 - 10/2010
82	Medulloblastoma 01/2022 - 10/2010
39	Glioma (Gliomas) 06/2022 - 09/2012
26	Ependymoma 01/2022 - 11/2011
19	Glioblastoma (Glioblastoma Multiforme) 12/2021 - 01/2012
18	Brain Neoplasms (Brain Tumor) 11/2021 - 08/2010
17	Astrocytoma (Pilocytic Astrocytoma) 06/2021 - 11/2011
11	Carcinogenesis 01/2022 - 04/2012
9	Primitive Neuroectodermal Tumors (PNET) 01/2021 - 11/2010
6	Neoplasm Metastasis (Metastasis) 01/2019 - 04/2012
5	Disease Progression 06/2022 - 02/2016
5	Chromothripsis 01/2022 - 08/2012
4	Rhabdoid Tumor (Rhabdoid Tumors) 01/2022 - 01/2017
4	Neuroblastoma 01/2022 - 01/2016
4	Genomic Instability 01/2022 - 06/2016
4	Meningioma (Meningiomas) 12/2021 - 03/2013
4	Oligodendroglioma 06/2021 - 02/2014
3	Diffuse Intrinsic Pontine Glioma 01/2021 - 01/2018
3	Sarcoma (Soft Tissue Sarcoma) 12/2020 - 01/2016
3	Pinealoma (Pineoblastoma) 01/2020 - 09/2012
2	Osteosarcoma (Osteogenic Sarcoma) 01/2022 - 01/2017
2	Li-Fraumeni Syndrome 01/2022 - 01/2017
2	Residual Neoplasm 12/2021 - 01/2018
2	Exanthema (Rash) 09/2020 - 01/2019
2	Chromosomal Instability (Chromosome Stability) 01/2020 - 01/2010
2	Nervous System Neoplasms (Neoplasms, Nervous System) 01/2019 - 03/2015
2	Typical Teratoid Rhabdoid Tumor 01/2019 - 12/2012
2	Choroid Plexus Neoplasms (Choroid Plexus Tumor) 03/2016 - 01/2015
2	Chromosome Aberrations (Chromosome Abnormalities) 11/2010 - 08/2010
1	Brain Stem Neoplasms (Brain Stem Tumor) 01/2022
1	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 12/2021

Drug/Important Bio-Agent (IBA)

30	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2010
29	Biological ProductsIBA 10/2021 - 08/2010
25	Biomarkers (Surrogate Marker)IBA 06/2022 - 11/2010
24	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 07/2011
21	Pharmaceutical PreparationsIBA 01/2022 - 06/2011
18	Histones (Histone)IBA 01/2022 - 01/2012
18	RNA (Ribonucleic Acid)IBA 11/2021 - 08/2012
16	MicroRNAs (MicroRNA)IBA 12/2021 - 11/2010
14	ChromatinIBA 01/2021 - 01/2012
13	Messenger RNA (mRNA)IBA 10/2021 - 10/2010
9	Formaldehyde (Formol)FDA Link 01/2020 - 11/2013
9	ParaffinIBA 11/2019 - 11/2013
8	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 06/2021 - 07/2013
8	dipinacoline glutamateIBA 01/2021 - 09/2012
7	ProteomeIBA 01/2022 - 06/2015
7	Transcription Factors (Transcription Factor)IBA 01/2022 - 07/2014
7	Phosphotransferases (Kinase)IBA 01/2021 - 01/2015
6	Lysine (L-Lysine)FDA Link 01/2022 - 03/2013
5	NucleotidesIBA 11/2021 - 01/2016
5	Temozolomide (Temodar)FDA LinkGeneric 01/2021 - 01/2018
5	Small Interfering RNA (siRNA)IBA 11/2019 - 10/2010
5	CateninsIBA 01/2019 - 11/2010
4	Dactinomycin (Actinomycin)FDA LinkGeneric 09/2021 - 09/2016
4	Histone Deacetylase InhibitorsIBA 01/2021 - 11/2011
4	Mitogen-Activated Protein KinasesIBA 09/2020 - 08/2013
3	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2021 - 12/2013
3	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2018
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2017 - 11/2011
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 12/2021
2	Polycomb Repressive Complex 2IBA 01/2022 - 11/2019
2	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 10/2016
2	Carboplatin (JM8)FDA LinkGeneric 01/2022 - 10/2018
2	entinostat (MS 275)IBA 01/2021 - 06/2020
2	Indicators and Reagents (Reagents)IBA 01/2021 - 11/2012
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021 - 02/2016
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2020 - 11/2012
2	Vorinostat FDA Link 12/2019 - 11/2011
2	hydrogen sulfite (bisulfite)IBA 05/2019 - 03/2016
2	EnzymesIBA 01/2019 - 07/2013
2	MethyltransferasesIBA 01/2019 - 01/2018
2	1,4-dinitro-2-methyl-2-buteneIBA 01/2019 - 12/2016
2	Amino Acids FDA Link 01/2018 - 07/2013
2	IsotopesIBA 01/2018 - 06/2015
2	Carrier Proteins (Binding Protein)IBA 01/2017 - 10/2014
2	RNA Helicases (RNA Helicase)IBA 05/2016 - 08/2012
2	NestinIBA 01/2016 - 11/2012
2	Pyruvate KinaseIBA 08/2015 - 06/2015
1	human MIRN376A1 microRNAIBA 06/2022
1	sonidegibIBA 01/2022
1	Etoposide (VP 16)FDA LinkGeneric 01/2022
1	Dyneins (Dynein)IBA 01/2022
1	Proto-Oncogene Proteins c-etsIBA 01/2022
1	Long Noncoding RNAIBA 01/2022
1	IonsIBA 12/2021
1	CarbonIBA 12/2021

Therapy/Procedure

67	Therapeutics 01/2022 - 11/2010
19	Drug Therapy (Chemotherapy) 01/2022 - 11/2011
12	Radiotherapy 01/2022 - 09/2012
6	Investigational Therapies (Experimental Therapy) 01/2021 - 01/2016
5	Precision Medicine 06/2022 - 01/2016
4	Transplantation 01/2019 - 11/2011
3	Aftercare (After-Treatment) 01/2022 - 01/2016
3	Chemoradiotherapy 01/2021 - 01/2016
3	Ligation 01/2018 - 05/2013
2	Transcutaneous Electric Nerve Stimulation (TENS) 01/2022 - 06/2016
2	Immunotherapy 01/2021 - 11/2019
2	Craniospinal Irradiation 01/2019 - 01/2016
1	Heavy Ion Radiotherapy 12/2021